Sign Up Free
Socialwider is all about social networking, sharing with friends and millions of people.

Tamoxifen citrate, white powder

Tamoxifen citrate, white powder



Tamoxifen has been shown to protect bone from estrogen-deficiency bone loss and lower plasma cholesterol in the rat. A 10 µM solution has exhibited fungicidal activity (optimal pH 7,5) against yeast cells of C. albicans. It has been implemented in liver carcinogenesis in rats.

Other actions of tamoxifen are: Reduction of plasma levels of insulin-like growth factor; Induction of cells surrounding cancer cells to secrete transforming growth factor b; Inhibition of membrane lipid peroxidation probably by decreasing membrane fluidity.

Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.

Soluble in methanol (50 mg/mL with heat) or ethanol (10 mg/mL with sonication); very slightly soluble in water (0.3 mg/L at 20 °C; the pH is approximately 3.0-3.5), 0.02 N HCl (0.2 mg/mL at 37 °C), acetone or chloroform.https://www.aasraw.com/products/tamoxifen-citrate-...
Captcha Challenge
Reload Image
Type in the verification code above
TOP